실험적 구루병 백루의 치아 급 경골에 관한 병리 조직학적 연구
Histopathologic study on teeth and tibial bone of the experimental richatic rats
오창민, 조여일,
소속 상세정보
오창민 ( ) - 조선대학교 의과대학 치료방사선과학교실
조여일 ( ) - 조선대학교
KMID : 0360119930150020137
Abstract
The purpose of this study was to observe the effect on teeth nad tibia bone histopathologically in rats by the richitogenic diet. For this purpose, 48 sprague-dewley rats, weighing 80g or more, divided into 6 groups, and sacrificed on the 1st,
2nd,
3rd,
4th, 5th, 6th weeks after experiments respectively.
The tissues contain tooth, and tibial bone were fixed in 10% normal formalin solution, decalcified in Plank-Rychlo solution, embedded in paraffin, sectioned in 6-8μ as usual manner, the tissues were stained in hematoxylin eosin, and examined
hisopathologically.
@ES Follow results were attained
@EN 1. Pyknotic appearance of odontoblastic layer was noticed on the lst week, and increased on the 2nd weks, and it is appared that degeneration and dearrangements of odontoblosts on the 4 weeks. But a little recovered on the 6th weeks.
2. The thickness of predentin layer was increased on the 2nd weeks, and increased remarkedly on the 3rd weeks and reached the maximum on the 5th weeks.
3. The interglobular dentin was appeared in spotty shape on the 2nd weeks, and increased on the 4th, 5th, weeks, and large amount of inter-globular dentin was appearanced on the 6th weeks.
4. It is appared that enamel hypoplasia on the 4th weeks.
5. Epiphyseal and metaphyseal plate of tibia was increased from/on the 2nd weeks, increased maximumly on the 5th weeks.
And pyknotic, dearrangements, and hyperchromatic appearances of chondrocytes on the plate were increased on the lst week.
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